HAVCR2/TIM-3 Monoclonal Antibody, PE-Cy5.5 Conjugated

Catalogue Number: BSM-43034M-PE-CY5.5-BSS

Manufacturer:Bioss Inc
Type:Monoclonal Primary Antibody - Conjugated
Alias:TIM-3; Tim 3; TIM3; TIMD-3; TIMD3; HAVR2_HUMAN; Hepatitis A virus cellular receptor 2; HAVcr-2; T-cell immunoglobulin and mucin domain-containing protein 3; T-cell immunoglobulin mucin receptor 3; T-cell membrane protein 3; CD366
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 5D12
Isotype: IgG
Immunogen: Recombinant human TIM-3 protein
Application: WB

Description

Description: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]

Additional Text

Gene Name

HAVCR2

Gene ID

84868

Uniprot ID

Q8TDQ0

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

488nm/694nm