PGC Monoclonal Antibody, PE-Cy5.5 Conjugated
Catalogue Number: BSM-43143M-PE-CY5.5-BSS
| Manufacturer: | Bioss Inc |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | PEPC_HUMAN; Gastricsin; EC:3.4.23.3; Pepsinogen C; PEPC; PGII; progastricsin |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant human PGC protein |
| Application: | WB |
Description
Description: This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1. [provided by RefSeq, Oct 2009].
Additional Text
Gene Name
PGC
Gene ID
5225
Uniprot ID
P20142
Purification
Protein A purified
Antibody Clonality
Monoclonal
Modification
Unmodified
Concentration
1 mg/ml
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
488nm/694nm
BSM-43143M-PE-CY5.5 Datasheet
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