Alas1 (1G11) Monoclonal Antibody
Catalogue Number: BSM-52012R-BSS
BSM-52012R Image
BSM-52012R Image
BSM-52012R Image
BSM-52012R Image
Lane 1: JAR lysates; Lane 2: HUVEC lysates; Lane 3: Hela lysates probed with Alas1 (1G11) Monoclonal Antibody (bsm-52012R) at 1:1000.
BSM-52012R Image
HepG2 cells were stained with Alas1 (1G11) Monoclonal Antibody (bsm-52012R) at 1:200 in PBS and incubated for overnight at 4C, followed by secondary antibody incubation, DAPI staining of the nuclei and detection
BSM-52012R Image
Lane 1: Human JAR cell lysates; Lane 2: Human Huvec cell lysates; Lane 3: Human Hela cell lysates; Lane 4: Human HepG2 cell lysates ; Lane 5: Human MCF-7 cell lysates; Lane 6: Human K562 cell lysates; Lane 7: Human Raji cell lysates probed with Alas1 (1G11) Monoclonal Antibody, Unconjugated (bsm-52012R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Ph: | 7.4 |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | 5-aminolevulinate synthase, nonspecific, mitochondrial; ALAS1; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1; ALAS1; ALAS3; ALASH; OK/SW-cl.121 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 1G11 |
| Isotype: | IgG |
| Immunogen: | Recombinant human Alas1 protein, around C-terminal 200aa. |
| Application: | ICC, IF, WB |
Description
Description: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]
Additional Text
Gene Name
ALAS1
Gene ID
211
Uniprot ID
P13196
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
bsm-52012R Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations