Catalogue Number: BSM-52062R-BSS
Manufacturer: | Bioss Inc |
Shelf Life: | 12 months |
Ph: | 7.4 |
Type: | Monoclonal Primary Antibody - Unconjugated |
Alias: | Keratin, type II cytoskeletal 4; KRT4 |
Shipping Condition: | Blue Ice |
Unit(s): | 100 ul |
Host name: | Rabbit |
Clone: | 2F9 |
Isotype: | IgG |
Immunogen: | Recombinant human Cytokeratin 4 protein, around 350-480aa. |
Application: | ICC, IF, IHC-P, WB |
Description: Defects in KRT4 are a cause of white sponge nevus of cannon (WSN) [MIM:193900]. WSN is a rare autosomal dominant disorder which predominantly affects non-cornified stratified squamous epithelia. Clinically, it is characterized by the presence of soft, white, and spongy plaques in the oral mucosa. The characteristic histopathologic features are epithelial thickening, parakeratosis, and vacuolization of the suprabasal layer of oral epithelial keratinocytes. Less frequently the mucous membranes of the nose, esophagus, genitalia and rectum are involved.
KRT4
P19013
3851
Protein A purified
1 ug/ul
Monoclonal
Unmodified
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.