HDAC4 (6B10) Monoclonal Antibody, AbBy Fluor-555 Conjugated

Catalogue Number: BSM-52085R-BF555-BSS

Manufacturer:Bioss Inc
Type:Monoclonal Primary Antibody - Conjugated
Alias:HDAC4Ser246; HDAC4S246; p-HDAC4Ser246; p-HDAC4S246; HD 4; HD4; HDAC 4; HDAC A; HDACA; Histone Deacetylase 4; Histone Deacetylase A; KIAA0288; EC 3.5.1.98; HA6116; HDA4_CAEEL; Histone deacetylase 4; CeHDA-7; Histone deacetylase 7.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: 6B10
Isotype: IgG
Immunogen: Recombinant human HDAC4 protein, around C-terminal 100aa.
Application: WB

Description

Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Additional Text

Gene ID

9759

Gene Name

HDAC4

Uniprot ID

P56524

Purification

Protein A purified

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

553nm/568nm