HDAC7 Recombinant Antibody, PE-Cy5.5 Conjugated
Catalogue Number: BSM-52087R-PE-CY5.5-BSS
| Manufacturer: | Bioss Inc |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Histone deacetylase 7; HDAC7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 3H7 |
| Isotype: | IgG |
| Immunogen: | Recombinant human HDAC7 protein, around N-terminal 150aa. |
| Application: | WB |
Description
Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene. Positively regulates the transcriptional repressor activity of FOXP3 (PubMed:17360565).
Additional Text
Gene ID
51564
Gene Name
HDAC7
Uniprot ID
Q8WUI4
Purification
Protein A purified
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
488nm/694nm
BSM-52087R-PE-CY5.5 Datasheet
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