HDAC8 Recombinant Antibody, AbBy Fluor-555 Conjugated

Catalogue Number: BSM-52088R-BF555-BSS

Manufacturer:Bioss Inc
Type:Recombinant Monoclonal
Alias:HD8; WTS; RPD3; CDA07; CDLS5; MRXS6; HDACL1; Histone deacetylase 8; HDAC8
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant human HDAC8 protein, around N-terminal 150aa.
Application: IF, WB

Description

Description: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regulating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility.

Additional Text

Gene Name

HDAC8

Gene ID

55869

Uniprot ID

Q9BY41

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

553nm/568nm