HIF-1 beta Recombinant Antibody, PE-Cy7 Conjugated

Catalogue Number: BSM-52092R-PE-CY7-BSS

Manufacturer:Bioss Inc
Type:Monoclonal Primary Antibody - Conjugated
Alias:HIF1B; TANGO; bHLHe2; HIF1BETA; HIF-1beta; HIF1-beta; HIF-1-beta; Aryl hydrocarbon receptor nuclear translocator; ARNT protein; Class E basic helix-loop-helix protein 2; Dioxin receptor, nuclear translocator; Hypoxia-inducible factor 1-beta; ARNT
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: 3F5
Isotype: IgG
Immunogen: Recombinant human HIF-1 beta protein, around 600-700aa.
Application: IHC-P, WB

Description

Description: Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Additional Text

Gene ID

405

Gene Name

ARNT

Uniprot ID

P27540

Purification

Protein A purified

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

488nm/780nm