IRF2 (5F2) Monoclonal Antibody
Catalogue Number: BSM-52115R-BSS
BSM-52115R Image
bsm-52115R Image
BSM-52115R Image
A549 cells were stained with IRF2 (5F2) Monoclonal Antibody (bsm-52115R) at [1:200] incubated overnight at 4C, followed by secondary antibody incubation, DAPI staining of the nuclei and detection.
bsm-52115R Image
Human lung lysates probed with IRF2 (5F2) Monoclonal Antibody (bsm-52115R) at 1:1000 overnight at 4˚C. Followed by a conjugated secondary antibody.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Ph: | 7.4 |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | IRF-2; Interferon regulatory factor 2; IRF2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 5F2 |
| Isotype: | IgG |
| Immunogen: | Recombinant human IRF2 protein, around C-terminal 100aa. |
| Application: | ICC, IF, WB |
Description
Description: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
Additional Text
Gene Name
IRF2
Uniprot ID
P14316
Gene ID
3660
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
bsm-52115R Datasheet
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