PI 3 Kinase p85 alpha (2G4) Monoclonal Antibody
Catalogue Number: BSM-52216R-BSS
BSM-52216R Image
BSM-52216R Image
bsm-52216R Image
BSM-52216R Image
HeLa cells were stained with PI 3 Kinase p85 alpha (2G4) Monoclonal Antibody (bsm-52216R) at [1:200] incubated overnight at 4C, followed by secondary antibody incubation, DAPI staining of the nuclei and detection.
BSM-52216R Image
Lane 1: Mouse Cerebrum lysates; Lane 2: Mouse Heart lysates; Lane 3: Mouse Spleen lysates; Lane 4: Rat Cerebrum lysates; Lane 5: Human Jurkat cell lysates; Lane 6: Human K562 cell lysates; Lane 7: Human MOLT-4 cell lysates; Lane 8: Human HL-60 cell lysates probed with PI 3 Kinase p85 alpha Monoclonal Antibody, Unconjugated (bsm-52216R ) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37°C.
bsm-52216R Image
Lane 1: MCF-7; Lane 2: Raji lysate probed with PI 3 Kinase p85 alpha (2G4) Monoclonal Antibody (bsm-52216R) at 1:1000 overnight at 4˚C. Followed by a conjugated secondary antibody .
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 2G4 |
| Isotype: | IgG |
| Immunogen: | Recombinant human PI 3 Kinase p85 alpha protein, around 600-700aa. |
| Application: | ICC, IF, WB |
Description
Description: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p11 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.
Additional Text
Gene Name
PIK3R1
Uniprot ID
P27986
Gene ID
5295
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Specificity
p85; AGM7; GRB1; IMD36; p85-ALPHA; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha; PIK3R1
Storage Note
Store at -20°C for 12 months.
BSM-52216R Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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