Integrin beta 1 (1G11) Monoclonal Antibody
Catalogue Number: BSM-52247R-BSS
BSM-52247R Image
BSM-52247R Image
BSM-52247R Image
BSM-52247R Image
BSM-52247R Image
Lane 1: Hela; Lane 2: NIH/3T3; Probed with Integrin beta 1 (1G11) Monoclonal Antibody (bsm-52247R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-52247R Image
Paraformaldehyde-fixed and paraffin-embedded human liver cancer tissue incubated with Integrin beta 1 (1G11) Monoclonal Antibody (bsm-52247R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-52247R Image
Paraformaldehyde-fixed and paraffin-embedded human colon cancer tissue incubated with Integrin beta 1 (1G11) Monoclonal Antibody (bsm-52247R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-52247R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse stomach tissue incubated with Integrin beta 1 (1G11) Monoclonal Antibody (bsm-52247R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Integrin beta-1, Fibronectin receptor subunit beta, Glycoprotein Iia, VLA-4 subunit beta, CD_antigen: CD29, GPIIA, ITGB1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 1G11 |
| Isotype: | IgG |
| Immunogen: | Recombinant Human Integrin beta 1 between 1 to 250 amino acids |
| Application: | IHC-P, WB, IHC |
Description
Description: Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-1/beta-1 and alpha-2/beta-2 recognize the proline-hydroxylated sequence G-F-P-G-E-R in collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Alpha-4/beta-1 recognizes one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Integrin alpha-4/beta-1 is a receptor for VCAM1. It recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. It recognizes the sequence A-E-I-D-G-I-E-L in cytotactin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform beta-1B interferes with isoform beta-1A resulting in a dominant negative effect on cell adhesion and migration (in vitro). In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Additional Text
Gene ID
3688
Gene Name
ITGB1
Uniprot ID
P05556
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-52247R Datasheet
SUPPORT
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DELIVERY
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