Integrin alpha 6 Recombinant Antibody, AbBy Fluor-555 Conjugated

Catalogue Number: BSM-52265R-BF555-BSS

Manufacturer:Bioss Inc
Type:Recombinant Monoclonal
Alias:Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f; ITGA6
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Recombinant Human Integrin alpha 6 between 1 to 100 amino acids
Application: IF, WB

Description

Description: Integrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets. Integrin alpha-6/beta-1 (ITGA6:ITGB1) is present in oocytes and is involved in sperm-egg fusion. Integrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

Additional Text

Gene Name

ITGA6

Gene ID

3655

Uniprot ID

P23229

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

553nm/568nm