DLG4 (1H8) Monoclonal Antibody

Catalogue Number: BSM-52272R-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Disks large homolog 4; Postsynaptic density protein 95; Synapse-associated protein 90; PSD-95; SAP-90; SAP90; Disks large homolog 4; discs large MAGUK scaffold protein 4; DLG4
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: 1H8
Isotype: IgG
Immunogen: Recombinant human PSD95 around N-terminus
Application: FC, ICC, IF, IHC-P, WB

Description

Description: Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B (By similarity).

Additional Text

Gene Name

DLG4

Uniprot ID

P78352

Gene ID

1742

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C for 12 months.