Caspase 2 (2B1) Monoclonal Antibody
Catalogue Number: BSM-52281R-BSS
BSM-52281R Image
BSM-52281R Image
BSM-52281R Image
BSM-52281R Image
BSM-52281R Image
BSM-52281R Image
BSM-52281R Image
BSM-52281R Image
293 cell lysates probed with Caspase 2 (2B1) Monoclonal Antibody (bsm-52281R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-52281R Image
Flow cytometric analysis of Jurkat cells with Caspase 2 (2B1) Monoclonal Antibody (bsm-52281R) at 1:50 dilution followed by secondary antibody incubation (red), compared with an unlabeled control (cells without incubation with primary antibody; black).
BSM-52281R Image
IF(ICC) staining with Caspase 2 (2B1) Monoclonal Antibody (bsm-52281R) at 1:100 in HeLa cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
BSM-52281R Image
IF(ICC) staining with Caspase 2 (2B1) Monoclonal Antibody (bsm-52281R) at 1:100 in A549 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
BSM-52281R Image
Paraformaldehyde-fixed and paraffin-embedded Human lung cancer tissue incubated with Caspase 2 (2B1) Monoclonal Antibody (bsm-52281R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-52281R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse kidney tissue incubated with Caspase 2 (2B1) Monoclonal Antibody (bsm-52281R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-52281R Image
Paraformaldehyde-fixed and paraffin-embedded Human kidney tissue incubated with Caspase 2 (2B1) Monoclonal Antibody (bsm-52281R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Caspase-2; Neural precursor cell expressed developmentally down-regulated protein 2; Protease ICH-1; CASP-2; NEDD-2; Caspase-2 subunit p18 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 2B1 |
| Isotype: | IgG |
| Immunogen: | Recombinant human Caspase-2 between 150 to 350 amino acids |
| Application: | FC, ICC, IF, IHC-P, WB |
Description
Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Might function by either activating some proteins required for cell death or inactivating proteins necessary for cell survival. Associates with PIDD1 and CRADD to form the PIDDosome, a complex that activates CASP2 and triggers apoptosis in response to genotoxic stress.
Additional Text
Gene Name
CASP2
Gene ID
835
Uniprot ID
P42575
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-52281R Datasheet
SUPPORT
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PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations