Caspase-9 (2A7) Monoclonal Antibody
Catalogue Number: BSM-52314R-BSS
BSM-52314R Image
BSM-52314R Image
BSM-52314R Image
BSM-52314R Image
BSM-52314R Image
BSM-52314R Image
BSM-52314R Image
Lane 1: Jurkat; Lane 2: Hela; Lane 3: C2C12 lysate probed with Caspase-9 (2A7) Monoclonal Antibody (bsm-52314R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-52314R Image
IF(ICC) staining with Caspase-9 (2A7) Monoclonal Antibody (bsm-52314R) at 1:300 in HeLa cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
BSM-52314R Image
IF(ICC) staining with Caspase-9 (2A7) Monoclonal Antibody (bsm-52314R) at 1:300 in HepG2 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
BSM-52314R Image
IF(ICC) staining with Caspase-9 (2A7) Monoclonal Antibody (bsm-52314R) at 1:300 in A549 cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
BSM-52314R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse spleen tissue incubated with Caspase-9 (2A7) Monoclonal Antibody (bsm-52314R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-52314R Image
Paraformaldehyde-fixed and paraffin-embedded Human tonsil tissue incubated with Caspase-9 (2A7) Monoclonal Antibody (bsm-52314R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Caspase-9; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; ICE-like apoptotic protease 6; CASP-9; APAF-3; ICE-LAP6; CASP9 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 2A7 |
| Isotype: | IgG |
| Immunogen: | Recombinant human Caspase-9 between 200 to 350 amino acids |
| Application: | ICC, IF, IHC-P, WB |
Description
Description: Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.
Additional Text
Gene Name
CASP9
Gene ID
842
Uniprot ID
P55211
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-52314R Datasheet
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