NADPH oxidase 4 Recombinant Antibody

Catalogue Number: BSM-52390R-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Alias:NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, KOX-1, NOX4, RENOX
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: 2A4
Isotype: IgG
Immunogen: Recombinant human NADPH oxidase 4 between 500 to C-terminus
Application: IF, IHC-P, WB, IHC-Fr

Description

Description: Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.

Additional Text

Gene Name

NOX4

Uniprot ID

Q9NPH5

Gene ID

50507

Purification

Protein A purified

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.