PKC beta 2 (10A1) Monoclonal Antibody
Catalogue Number: BSM-52464R-BSS
BSM-52464R Image
BSM-52464R Image
BSM-52464R Image
BSM-52464R Image
BSM-52464R Image
Flow cytometric analysis of HeLa cells with PKC beta 2 (10A1) Monoclonal Antibody (bsm-52464R) at 1:50 dilution followed by secondary antibody incubation (red), compared with an unlabeled control (cells without incubation with primary antibody; black).
BSM-52464R Image
Raji cells Probed with PKC beta 2 (10A1) Monoclonal Antibody (bsm-52464R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-52464R Image
IF(ICC) staining with PKC beta 2 (10A1) Monoclonal Antibody (bsm-52464R) at 1:100 in SH-SY5Y cells (green). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
BSM-52464R Image
Paraformaldehyde-fixed and paraffin-embedded Human spleen tissue incubated with PKC beta 2 (10A1) Monoclonal Antibody (bsm-52464R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Protein kinase C beta type, PKC-B, PKC-beta, Prkcb, Pkcb, Prkcb1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 10A1 |
| Isotype: | IgG |
| Immunogen: | Human PKC beta 2 between 600 to C-terminus |
| Application: | FC, ICC, IF, IHC-P, WB, IHC |
Description
Description: Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional PKC isoforms (_, _I, _II and _) and novel PKC isoforms. Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC _ and are independent of Ca2+. On the other hand, nPKC _ and _, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.
Additional Text
Gene ID
5579
Gene Name
PRKCB
Uniprot ID
P05771
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-52464R Datasheet
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