14-3-3 (9C4) Monoclonal Antibody

Catalogue Number: BSM-52728R-BSS

Manufacturer:Bioss Inc
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Alias:14-3-3 protein beta/alpha, Protein 1054, Protein kinase C inhibitor protein 1, 14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAB, YWHAZ
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: 9C4
Isotype: IgG
Immunogen: Recombinant protein of Human 14-3-3 between 200-300 amino acids
Application: IHC-P, WB

Description

Description: Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by SRPK2.

Additional Text

Purification

Protein A purified

Gene ID

7529; 7534

Uniprot ID

P31946, P63104

Concentration

1 ug/ul

Gene Name

YWHAB, YWHAZ

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.