TSG101 Recombinant Antibody, RBITC Conjugated
Catalogue Number: BSM-52746R-RBITC-BSS
| Manufacturer: | Bioss Inc |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 6C3 |
| Isotype: | IgG |
| Immunogen: | Human TSG101 between 1 to 100 amino acids |
| Application: | FC, ICC, IF, WB |
Description
Description: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
Additional Text
Gene Name
TSG101
Uniprot ID
Q99816
Gene ID
7251
Purification
Protein A purified
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
570nm/595nm
BSM-52746R-RBITC Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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