ABCG2 Recombinant Antibody, AbBy Fluor-405 Conjugated
Catalogue Number: BSM-52821R-BF405-BSS
| Manufacturer: | Bioss Inc |
| Type: | Recombinant Monoclonal |
| Alias: | ATP-binding cassette sub-family G member 2, Breast cancer resistance protein, CDw338, Mitoxantrone resistance-associated protein, Placenta-specific ATP-binding cassette transporter, URate exporter, CD_antigen: CD338, ABCG2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 20 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Human ABCG2 aa 1-400 |
| Application: | FC, ICC, IF, WB |
Description
Description: High-capacity urate exporter functioning in both renal and extrarenal urate excretion. Plays a role in porphyrin homeostasis as it is able to mediates the export of protoporhyrin IX (PPIX) both from mitochondria to cytosol and from cytosol to extracellular space, and cellular export of hemin, and heme. Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. Implicated in the efflux of numerous drugs and xenobiotics: mitoxantrone, the photosensitizer pheophorbide, camptothecin, methotrexate, azidothymidine (AZT), and the anthracyclines daunorubicin and doxorubicin.
Additional Text
Gene Name
ABCG2
Uniprot ID
Q9UNQ0
Gene ID
9429
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
401nm/421nm
BSM-52821R-BF405 Datasheet
SUPPORT
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