FMRP (1B6) Monoclonal Antibody
Catalogue Number: BSM-52945R-BSS
BSM-52945R Image
BSM-52945R Image
BSM-52945R Image
BSM-52945R Image
BSM-52945R Image
BSM-52945R Image
Lane 1: Hela cells lysates; Lane 2: K562 cells lysates; Probed with FMRP (1B6) Monoclonal Antibody (bsm-52945R) at 1:500 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-52945R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse colon tissue incubated with FMRP (1B6) Monoclonal Antibody (bsm-52945R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-52945R Image
Paraformaldehyde-fixed and paraffin-embedded Rat brain tissue incubated with FMRP (1B6) Monoclonal Antibody (bsm-52945R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-52945R Image
IF(ICC) staining with FMRP (1B6) Monoclonal Antibody (bsm-52945R) at 1:200 in HepG2 cells (red). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
BSM-52945R Image
IF(ICC) staining with FMRP (1B6) Monoclonal Antibody (bsm-52945R) at 1:200 in SH-SY5Y cells (red). The nuclear counterstain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilized with 0.25% Triton X100/PBS.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Synaptic functional regulator FMR1, Fragile X mental retardation protein 1, FMRP, Protein FMR-1, FMR1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 1B6 |
| Isotype: | IgG |
| Immunogen: | Human FMRP aa 1-100 |
| Application: | ICC, IF, IHC-P, WB, IHC |
Description
Description: Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).
Additional Text
Gene Name
FMR1
Uniprot ID
Q06787
Gene ID
2332
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-52945R Datasheet
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DELIVERY
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