ORC2 (5C3) Monoclonal Antibody
Catalogue Number: BSM-53025M-BSS
BSM-53025M Image
BSM-53025M Image
RIPA cell lysates from HeLa cells (30 µg) were analysed by Western blot using ORC2 (5C3) Monoclonal Antibody (bsm-53025M) diluted 1:500 in PBS-Tween containing 10% milk. The position of the protein of interest is indicated on the right (expected size: 66 kDa); the marker (in kDa) is shown on the left.
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Preservative: | 0.05% Sodium azide |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | ORC2L, Origin recognition complex subunit 2, ORC2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Mouse |
| Clone: | 5C3 |
| Isotype: | IgG1 |
| Immunogen: | Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively |
| Application: | ICC, IF, WB |
Description
Description: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.
Additional Text
Gene Name
ORC2
Uniprot ID
Q13416
Gene ID
4999
Purification
Protein G purified
Antibody Clonality
Monoclonal
Concentration
0.6 ug/ul
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-53025M Datasheet
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