TNFRSF10B (1D8) Monoclonal Antibody
Catalogue Number: BSM-54027R-BSS
BSM-54027R Image
BSM-54027R Image
BSM-54027R Image
BSM-54027R Image
BSM-54027R Image
BSM-54027R Image
BSM-54027R Image
Lane 1: HL-60 Cells; Probed with TNFRSF10B (1D8) Monoclonal Antibody (bsm-54027R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-54027R Image
Paraformaldehyde-fixed and paraffin-embedded Human Tonsil tissue incubated with TNFRSF10B (1D8) Monoclonal Antibody (bsm-54027R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-54027R Image
Paraformaldehyde-fixed and paraffin-embedded Human Liver tissue incubated with TNFRSF10B (1D8) Monoclonal Antibody (bsm-54027R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-54027R Image
Paraformaldehyde-fixed and paraffin-embedded Human Colon Carcinoma tissue incubated with TNFRSF10B (1D8) Monoclonal Antibody (bsm-54027R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining.
BSM-54027R Image
Paraformaldehyde-fixed and paraffin-embedded Human Placenta tissue incubated with TNFRSF10B (1D8) Monoclonal Antibody (bsm-54027R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-54027R Image
Flow cytometric analysis of SW480 cells with TNFRSF10B (1D8) Monoclonal Antibody (bsm-54027R) at 1:100 dilution (red) compared with an unlabeled control (cells without incubation with primary antibody; black).
| Manufacturer: | Bioss Inc |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Tumor necrosis factor receptor superfamily member 10B, Death receptor 5, TNF-related apoptosis-inducing ligand receptor 2, TRAIL receptor 2, TRAIL-R2, CD262, TNFRSF10B, DR5, KILLER, TRAILR2, TRICK2, ZTNFR9 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | 1D8 |
| Isotype: | IgG |
| Immunogen: | Human DR5 aa 200 to the C-terminus |
| Application: | FC, IF, IHC-P, IP, WB |
Description
Description: Tumor necrosis factor (TNF) is a pleiotropic cytokine whose function is mediated by two distinct cell surface receptors, designated TNF-R1 and TNF-R2, which are expressed on most cell types. TNF function is primarily mediated through TNF-R1 signaling. Both receptors belong to the growing TNF receptor superfamily which includes FAS antigen and CD40. TNF-R1 contains a cytoplasmic motif, termed the "death domain," that has been found to be necessary for the transduction of the apoptotic signal. The death domain is also found in several other receptors, including FAS, DR2 (or TRUNDD), DR3 (Death Receptor 3), DR4 and DR5. TRUNDD, DR4 and DR5 are receptors for the apoptosis-inducing cytokine TRAIL. A non-death domain-containing receptor, designated decoy receptor (DcR1 or TRID), also specifically associates with TRAIL and may play a role in cellular resistance to apoptotic stimuli.
Additional Text
Gene Name
TNFRSF10B
Uniprot ID
O14763
Gene ID
8795
Purification
Protein A purified
Concentration
1 ug/ul
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C for 12 months.
bsm-54027R Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations