phospho-MLKL (Ser345) Recombinant Antibody
Catalogue Number: BSM-54104R-BSS
BSM-54104R Image
BSM-54104R Image
BSM-54104R Image
BSM-54104R Image
BSM-54104R Image
BSM-54104R Image
Lane 1: Mouse Spleen; Lane 2: Mouse Lung; Lane 3: Mouse Thymus; Probed with MLKL (Ser345) (7G4) Monoclonal Antibody (bsm-54104R) at 1:1000 overnight at 4°C followed by a conjugated secondary antibody for 60 minutes at 37°C.
BSM-54104R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse Lung tissue incubated with MLKL (Ser345) (7G4) Monoclonal Antibody (bsm-54104R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-54104R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse Liver tissue incubated with MLKL (Ser345) (7G4) Monoclonal Antibody (bsm-54104R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-54104R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse Colon tissue incubated with MLKL (Ser345) (7G4) Monoclonal Antibody (bsm-54104R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
BSM-54104R Image
Paraformaldehyde-fixed and paraffin-embedded Mouse Spleen tissue incubated with MLKL (Ser345) (7G4) Monoclonal Antibody (bsm-54104R) at 1:100, overnight at 4°C, followed by a conjugated secondary antibody and DAB staining. Counterstained with hematoxylin.
| Manufacturer: | Bioss Inc |
| Type: | Recombinant Monoclonal |
| Alias: | Phospho-MLKL (S345); pMLKL Ser345; Mixed lineage kinase domain-like protein, Mlkl |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 20 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL |
| Application: | IP, WB |
Description
Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Additional Text
Uniprot ID
Q9D2Y4
Gene ID
74568
Modification
Phosphorylated, Ser345
Purification
Protein A purified
Gene Name
MLKL
Antibody Clonality
Recombinant Monoclonal
Storage Note
Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
bsm-54104R Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations