PTGES3 (1A26) Monoclonal Antibody

Catalogue Number: BSM-54193R-BSS

Manufacturer:Bioss Inc
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23; cPGES; P23; TEBP.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: 1A26
Isotype: IgG
Immunogen: Synthetic peptide within human p23 aa 50-100
Application: ICC, IF, IHC-P, IP, WB, IHC

Description

Description: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

Additional Text

Gene ID

10728

Gene Name

PTGES3

Uniprot ID

Q15185

Purification

Protein A purified

Concentration

1 ug/ul

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.