TRAM2 Recombinant Antibody, RBITC Conjugated

Catalogue Number: BSM-61131R-RBITC-BSS

Manufacturer:Bioss Inc
Type:Recombinant Monoclonal
Alias:KIAA0057;TRAM like protein;Tram2;Translocating chain associating membrane protein 2;Translocation associated membrane protein 2.
Shipping Condition:Blue Ice
Unit(s): 100 ul, 20 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human TRAM2
Application: WB

Description

Description: Necessary for collagen type I synthesis. May couple the activity of the ER Ca2+ pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca2+ concentration at the site of collagen synthesis, and a high Ca2+ concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).

Additional Text

Gene Name

TRAM2

Gene ID

9697

Uniprot ID

Q15035

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

570nm/595nm