beta Arrestin 1 Recombinant Antibody, PE-Cy5 Conjugated
Catalogue Number: BSM-61185R-PE-CY5-BSS
| Manufacturer: | Bioss Inc |
| Type: | Recombinant Monoclonal |
| Alias: | ARRB1; ARB1; ARR1; Arrestin beta 1; Beta arrestin 1. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 20 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human beta Arrestin 1 |
| Application: | FC, WB |
Description
Description: Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta-arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation.
Additional Text
Gene Name
ARRB1
Gene ID
408
Uniprot ID
P49407
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
488nm/670nm
BSM-61185R-PE-CY5 Datasheet
SUPPORT
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PRODUCT
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