RhoA/B/C Recombinant Antibody, AbBy Fluor-350 Conjugated

Catalogue Number: BSM-61200R-BF350-BSS

Manufacturer:Bioss Inc
Type:Recombinant Monoclonal
Alias:ARH12, ARH6; ARH9; ARHA; ARHA2; H12; RHO12; Transforming protein RhoA; RHOA; RHOB; RHOC.
Shipping Condition:Blue Ice
Unit(s): 100 ul, 20 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human RhoA
Application: FC, ICC, IF, WB

Description

Description: RhoA , RhoB , RhoC is a small G protein of the Rho family. Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. The three mammalian Rho proteins (A, B and C) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.

Additional Text

Purification

Protein A purified

Uniprot ID

P08134, P61586, P62745

Gene ID

387; 388; 389

Gene Name

RHOA, RHOB, RHOC

Antibody Clonality

Recombinant Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

346nm/442nm