HP1 alpha Recombinant Antibody, RBITC Conjugated
Catalogue Number: BSM-61202R-RBITC-BSS
| Manufacturer: | Bioss Inc |
| Type: | Recombinant Monoclonal |
| Alias: | CBX5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 20 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human CBX5 |
| Application: | FC, ICC, IF, WB |
Description
Description: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Additional Text
Gene ID
23468
Gene Name
CBX5
Uniprot ID
P45973
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
570nm/595nm
BSM-61202R-RBITC Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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