NUMB Recombinant Antibody, AbBy Fluor-594 Conjugated

Catalogue Number: BSM-61410R-BF594-BSS

Manufacturer:Bioss Inc
Type:Recombinant Monoclonal
Alias:c14_5527; h Numb; Numb; Numb homolog; S171.
Shipping Condition:Blue Ice
Unit(s): 100 ul, 20 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human NUMB
Application: WB

Description

Description: Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling.

Additional Text

Gene Name

NUMB

Uniprot ID

P49757

Gene ID

8650

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

590nm/617nm