Catalogue Number: BSM-61410R-BF594-BSS
| Manufacturer: | Bioss Inc |
| Type: | Recombinant Monoclonal |
| Alias: | c14_5527; h Numb; Numb; Numb homolog; S171. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 20 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human NUMB |
| Application: | WB |
Description: Numb acts as a negative regulator of Notch signaling by promoting ubiquitination and degradation of Notch. The protein is asymmetrically segregated into one daughter cell during cell division, producing two daughter cells with different responses to Notch signaling and different cell fates. The localization of Numb can also be regulated by G-protein coupled receptor (GPCR) and PKC signaling.
NUMB
P49757
8650
Protein A purified
Recombinant Monoclonal
Unmodified
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
590nm/617nm