RNF8 Recombinant Antibody, AbBy Fluor-555 Conjugated

Catalogue Number: BSM-61658R-BF555-BSS

Manufacturer:Bioss Inc
Type:Recombinant Monoclonal
Alias:C3HC4 type zinc finger protein; RNF8.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human RNF8
Application: WB

Description

Description: E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.

Additional Text

Gene ID

9025

Gene Name

RNF8

Uniprot ID

O76064

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

553nm/568nm