SorLA Recombinant Antibody, PE-Cy7 Conjugated

Catalogue Number: BSM-62077R-PE-CY7-BSS

Manufacturer:Bioss Inc
Type:Recombinant Monoclonal
Alias:gp250; LR11; LRP9; SORL1; SorLA 1; SorLA.
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide derived from human Sortilin related receptor
Application: WB

Description

Description: Sorting receptor that directs several proteins to their correct location within the cell (Probable). Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated.

Additional Text

Gene ID

6653

Gene Name

SORL1

Uniprot ID

Q92673

Purification

Protein A purified

Antibody Clonality

Recombinant Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

488nm/780nm