BLNK Recombinant Antibody, AbBy Fluor-350 Conjugated
Catalogue Number: BSM-62608R-BF350-BSS
| Manufacturer: | Bioss Inc |
| Type: | Recombinant Monoclonal |
| Alias: | AGM4; BASH; Bca; BLNK; Ly57; Lyw57; SLP65. |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | KLH conjugated synthetic peptide derived from human BLNK |
| Application: | IF, WB |
Description
Description: Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes.
Additional Text
Gene ID
29760
Gene Name
BLNK
Uniprot ID
Q8WV28
Purification
Protein A purified
Antibody Clonality
Recombinant Monoclonal
Modification
Unmodified
Storage Note
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Excitation
346nm/442nm
BSM-62608R-BF350 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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