NPHS2 Monoclonal Antibody, AbBy Fluor-488 Conjugated

Catalogue Number: BSM-63061R-BF488-BSS

Manufacturer:Bioss Inc
Type:Monoclonal Primary Antibody - Conjugated
Alias:nephrosis 2, idiopathic, steroid resistant; NPHS2 gene; PDCN; Podocin; SRN1; PODO_HUMAN
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone: No
Isotype: IgG
Immunogen:
Application: IF, WB

Description

Description: Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.

Additional Text

Gene Name

NPHS2

Uniprot ID

Q9NP85

Gene ID

7827

Purification

Protein A purified

Antibody Clonality

Monoclonal

Modification

Unmodified

Storage Note

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Excitation

499nm/519nm