Annexin A1 Antibody
Catalogue Number: BSM-70334M-BSS
| Manufacturer: | Bioss Inc |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Annexin A1, Annexin I, Annexin-1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I1, Phospholipase A2 inhibitory protein p35, ANXA1, ANX1, LPC1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | M021 |
| Isotype: | IgG1 |
| Immunogen: | Clone M021 was generated from a proprietary antigen related to human Annexin A1 in the A549 lung carcinoma cell line. |
| Application: | IP, WB |
Description
Description: The Annexin family is composed of at least thirteen mammalian genes (Annexin A1-13). These proteins are characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner and a unique amino terminal region which may confer binding specificity. Annexins have roles in membrane fusion, endocytosis, secretion, and repair. Annexin A1 binds to cellular membranes in a calcium-dependent manner, promotes membrane fusion and endocytosis, and has been implicated as an anti-inflammatory mediator. Annexin A2 is a cytoskeletal calcium-dependent phospholipid binding protein, which has been shown to be a mediator of corticosteroid activity, a substrate for serine/threonine kinases and growth regulated tyrosine kinases, and may play a role in secretion. Annexin A5 is a PKC inhibitor, directly interacts with VEGFR2 receptor, and binds phosphatidylserine to inhibit blood coagulation. Annexin A6 reverses transformation of A431 cells after overexpression, and this effect may involve annexin A6 targeting of p120 RasGAP to the plasma membrane to inactivate Ras.
Additional Text
Gene Name
ANXA1
Uniprot ID
P04083
Gene ID
301
Purification
Protein G purified
Antibody Clonality
Monoclonal
Modification
Unmodified
Storage Note
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
BSM-70334M Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations