Complement C1q (Complement Component 1, q Subcomponent) (MaxLight 490)
Catalogue Number: C0010-02E-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3R9/2 |
| Isotype: | IgG1 |
| Immunogen: | Globular head domain of Complement C1q, purified from human plasma. |
| Application: | FC, IF, WB, IHC, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Human complement component 1, q subcomponent (C1q) is a 156kDa secreted protein. C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis.
Additional Text
Specificity
Recognizes human Complement C1q (C1q) at 156kD.
Purification
Protein A purified
Antibody Clonality
Monoclonal
C0010-02E-ML490 Datasheet
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