c-myc (Myc, myc-1, Cellular myelocytomatosis oncogene, Myc2, Niard, Nird, Transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog) (MaxLight 490)
Catalogue Number: C0035-09-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 9E10 |
| Isotype: | IgG1 |
| Immunogen: | Synthetic peptide corresponding to amino acids 408-437 of the Leucine zipper region of human c-myc AEEQKLISEEDLLRKRREQLKHKLEQLRNS. |
| Application: | ICC, IP, WB |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. c-myc is involved in the control of cell proliferation and differentiation. Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (k light chain); or 22 (l light chain) is described in Burkitt's lymphoma and other B-cell lympho-proliferative conditions. An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.
Additional Text
Gene Name
MYC
Gene ID
4609
Uniprot ID
P01106
Specificity
Recognizes and is specific for human c-myc and recombinant proteins containing the Myc epitope tag.
Purification
Protein G purified
Accession Number
NM_002467.3
Antibody Clonality
Monoclonal
C0035-09-ML490 Datasheet
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