Mouse anti Human CDC25A
Catalogue Number: C105M-EXA
| Manufacturer: | ExAlpha |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Dual specificity phosphatase Cdc25A; M-phase inducer phosphatase 1; MPIP1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | DCS121 |
| Isotype: | IgG2a |
| Immunogen: | |
| Application: | IP, WB |
Description
Description: The immunogen for the anti CDC25A was a purified recombinant CDC25A protein recognizing a 65kD protein. In the cell cycle of eukaryotes the M phase is initiated by maturation promoting factor (MPF), a protein kinase complex consisting of p34 cdc2, cyclin B, and p13. The activity of this complex is controlled by multiple levels of phosphorylation and dephosphorylation of the catalytic p34cdc2 component. CDC25A and CDC25B arep34cdc2 tyrosine phosphates. Dephosphorylation of p34cdc2 by these CDC25 proteins activates the MPF complex, initiating mitosis. Although expressed throughout the cell cycle, peak expression of CDC25A is in G1 of the cell cycle.
Additional Text
Gene Name
CDC25A
Gene ID
993
Uniprot ID
P30304
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
Western Blot, Immunoprecipitation at 1-10 ug/ml
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
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DELIVERY
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