CAR (Coxsackie Adenovirus Receptor) (MaxLight 650)
Catalogue Number: C1079-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2T6 |
| Isotype: | IgG1 |
| Immunogen: | Native human coxsackie virus adenovirus receptor protein. |
| Application: | ICC, WB |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. The coxsackie virus and adenovirus receptor (CAR) mediates cell attachment and infection by coxsackie B viruses and by a number of adenoviruses. CAR also mediates homotypic intercellular interactions. In polarized epithelial cells, CAR is closely associated with the tight junction, where it contributes to the barrier to paracellular flow of solutes and macromolecules. CAR's biological roles are not well defined, but emerging evidence suggests that it may function during embryonic development and in regulating cell proliferation.
Additional Text
Gene Name
CXADR
Uniprot ID
P78310
Gene ID
1525
Accession Number
NM_001338
Specificity
Recognizes human CAR at ~46kD. Species Crossreactivity: mouse and rat
Purification
Protein G purified
Antibody Clonality
Monoclonal
C1079-ML650 Datasheet
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