Anti-Human Caspase-3 Active Subunit (p17)
Catalogue Number: C1141-LET
| Manufacturer: | Leinco Technologies, Inc |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 0.2 mg |
| Host name: | |
| Clone: | C31.129 |
| Isotype: | |
| Immunogen: | |
| Application: | WB |
Description
Description: Caspase-3 is a member of the caspase family of cysteine proteases and plays a key role in mediating Fas (CD95) and tumor necrosis factor-1 (TNFR-1) induced apoptosis. Caspases can be divided into three groups: apoptotic initiators, apoptotic executioners, and inflammatory mediators.1,2 Caspase-3 is activated during apoptotic signaling events by upstream proteases including caspase 6 and caspase 8.3 Caspase-3 is thought to be essential for chromatin margination, DNA fragmentation and nuclear collapse during apoptosis.3
Additional Text
Concentration
0.5 mg/ml
Antibody Clonality
Monoclonal
Storage Note
This purified antibody is stable when stored at 2-8°C. Do not freeze.
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