Mouse anti Human p16 - ink4a
Catalogue Number: C170M-NMB
| Manufacturer: | Nordic MuBio |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | hp16; p16 ink4a; Cyclin dependent kinase inhibitor 2A, isoforms 1/2/3; Cyclin-dependent kinase 4 inhibitor A; CDK4I |
| Shipping Condition: | RT |
| Unit(s): | 100 ug |
| Host name: | Mouse |
| Clone: | DCS50.1 |
| Isotype: | IgG1 |
| Immunogen: | A recombinant full length p16 protein recognizing a 16kDa protein |
| Application: | IP, WB, IHC |
Description
Description: The immunogen for the anti-human p16 was a recombinant full length p16 protein recognizing a 16kDa protein. The p16ink4a tumor suppressor protein shows no cross reactivity with the closely related inhibitors such as p15ink4b and p18ink4c. p16ink4a is a specific inhibitor of cdk4/cdk6, and is a tumor suppressor involved in the pathogenesis of a number of malignancies including melanoma and lung carcinoma. It can be used in immunohistochemistry as an indicator of HPV infection in cervical and head and neck (pre)malignancies.
Additional Text
Gene Name
CDKN2A
Gene ID
1029
Uniprot ID
P42771
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
Applications: Western Blot, Immunoflurescence, Immunoprecipitation (co-precipitates cdk4/cdk6)
Storage Note
Product should be stored at -20C. Aliquot to avoid freeze/thaw cycles
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations