Catenin, gamma (Plakoglobin) (MaxLight 550)

Catalogue Number: C2069-55-ML550-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	catenin (cadherin-associated protein), gamma 80kDa\|CTNNG\|desmoplakin III\|desmoplakin-3\|DP3\|DPIII\|junction plakoglobin\|PDGB\|PKGB
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	2Q239 (11E4)
Isotype:	IgG1
Immunogen:	Recombinant protein corresponding to human gamma-catenin
Application:	ICC, IP, WB, IHC

Overview
Datasheets

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. The catenins are polypeptides that bind to the conserved cytoplasmic tail of cadherins and are required for cadherin function. a-catenin is a 102kD protein that is associated with the cadherin indirectly through its interaction with b-catenin and g-catenin. b-Catenin and its homolog plakoglobin associate directly with the cadherin. Thus, the cell-cell adherens junction is a structure composed of the transmembrane cadherin, which is associated directly with either b-catenin or plakoglobin, which in turn assoctiates directly with a-catenin. a- Catenin then mediates the interaction between the cadherin-catenin complex and the actin cytoskeleton. a-Catenin has been characterized as a tumor suppressor, suggesting that it may have a regulatory function in relation to its structural role.

Additional Text

Gene Name

JUP

Gene ID

3728

Uniprot ID

P14923

Specificity

Recognizes recombinant human gamma-catenin.

Purification

Purified

Accession Number

NM_002230.1

Antibody Clonality

Monoclonal

C2069-55-ML550 Datasheet

Price

£979.00

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Quantity
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