Casein Kinase 2 alpha (CKIIa CK2A1, CSNK2A1) (APC)
Catalogue Number: C2085-63J-APC-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 9H211 (1AD9) |
| Isotype: | IgG1 |
| Immunogen: | Purified recombinant alpha-subunit of Casein Kinase 2. |
| Application: | ICC, IP, WB, DB, IHC |
Description
Description: Unlike most serine/threonine kinases, Casein Kinases (CKs) are not activated by specific stimuli, but are essentially constitutively active. CK1 autophosphorylates, causing inactivation, and protein phosphatases reactivate the kinase. The substrates of CKs are numerous, but their function is less clear, perhaps due to the absence of obvious regulation. CK1 isoforms are thought to be involved in the response to DNA damage, while CK2 levels are elevated in many types of cancer.
Additional Text
Gene ID
1457
Gene Name
CSNK2A1
Uniprot ID
P68400
Accession Number
NM_001895.3
Specificity
Recognizes the alpha-subunit of Casein Kinase 2. It binds specifically to the catalytic alpha-subunit of Casein Kinase 2 (CK-2a). Species Crossreactivity: human, mouse and rat.
Purification
Purified
Antibody Clonality
Monoclonal
C2085-63J-APC Datasheet
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