Casein Kinase 2 alpha (CKIIa CK2A1, CSNK2A1) (MaxLight 550)
Catalogue Number: C2085-63J-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 9H211 (1AD9) |
| Isotype: | IgG1 |
| Immunogen: | Purified recombinant alpha-subunit of Casein Kinase 2. |
| Application: | ICC, IP, WB, DB, IHC |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. Unlike most serine/threonine kinases, Casein Kinases (CKs) are not activated by specific stimuli, but are essentially constitutively active. CK1 autophosphorylates, causing inactivation, and protein phosphatases reactivate the kinase. The substrates of CKs are numerous, but their function is less clear, perhaps due to the absence of obvious regulation. CK1 isoforms are thought to be involved in the response to DNA damage, while CK2 levels are elevated in many types of cancer.
Additional Text
Gene ID
1457
Gene Name
CSNK2A1
Uniprot ID
P68400
Accession Number
NM_001895.3
Specificity
Recognizes the alpha-subunit of Casein Kinase 2. It binds specifically to the catalytic alpha-subunit of Casein Kinase 2 (CK-2a). Species Crossreactivity: human, mouse and rat.
Purification
Purified
Antibody Clonality
Monoclonal
C2085-63J-ML550 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations