CCR1 (Chemokine Receptor 1, CC-CCR-1) (APC)

Catalogue Number: C2100-16B-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	C-C chemokine receptor type 1\|C-C CKR-1\|CC-CKR-1\|CCR-1\|chemokine (C-C) receptor 1\|Cmkbr1\|macrophage inflammatory protein 1-alpha receptor\|MIP-1 alpha R\|MIP-1 alphaR\|MIP-1alpha-R\|Mip-1a-R\|RANTES-R
Shipping Condition:	Blue Ice
Unit(s):	100 Tests
Host name:	Rat
Clone:	11D85
Isotype:	IgG2b
Immunogen:	Recombinant protein corresponding to the extracellular regions at aa1-34, aa92-107, aa172-192 and aa265-281 of mouse CCR1 expressed in E. coli. Uniprot: P51675
Application:	FC, WB, FLISA

Overview
Datasheets

Description

Description: CCR1 (C-C chemokine receptor 1; also known as MIP-1a receptor and CD191) is a 43kD member of the G protein-coupled receptor 1 family of transmembrane proteins. Mouse CCR1 is expressed on osteoclasts, IL-13+ T cells, neutrophils, bone marrow-derived mast cells, eosinophils, monocytes, and vascular intimal smooth muscle cells. Multiple chemokines are reported to bind to CCR1. MIP-1a/CCL3 and RANTES/CCL5 are natural ligands, while CCL15, CCL9, and CCL23 are potent agonists after N-terminal processing. Mouse CCR1 is a seven transmembrane protein that is 355aa in length. It contains a 34aa N-terminal extracellular domain plus a 50aa C-terminal cytoplasmic tail. Over aa sequences 1-34, 92-107, 172-192, and 265-281 collectively, mouse CCR1 shares 76% and 89% aa identity with human and rat CCR1, respectively.

Additional Text

Caution

FOR RESEARCH USE ONLY

Uniprot ID

P51675

Gene Name

CCR1

Specificity

Recognizes mouse CCR1. In Direct ELISAs and Western Blots shows no crossreactivity with recombinant mouse CCR4, 5, or 8.

Purification

Protein G purified

Gene ID

12768

Antibody Clonality

Monoclonal

C2100-16B Datasheet

Price

£863.00

-

Quantity
Unit Size

Find out about delivery