Anti-Human CD62L - Purified

Catalogue Number: C2140-LET

Manufacturer:Leinco Technologies, Inc
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 500 ug
Host name:
Clone: DREG56
Isotype:
Immunogen:
Application: FC, IF, IHC-P, WB, Img

Description

Description: CD62L antibody, clone DREG56, recognizes CD62L, also known as L-selectin or LECAM-1, a 74-95 kDa type I transmembrane glycoprotein and cell adhesion molecule expressed on most circulating leukocytes1. Ligands for CD62L include CD34, GlyCAM-1, and MAdCAM-1, which require sialyation, fucosylation, and carbohydrate sulfation for recognition2,3. Ligand binding mediates tethering and rolling of leukocytes, facilitating entry into secondary lymphoid organs, including lymph nodes and Peyer's patches, via high endothelial venules (HEVs)1. CD62L is also expressed on human embryo trophoblasts and has been proposed to play a role in human embryo implantation4.

Additional Text

Concentration

0.5 mg/ml

Purification

Purified

Antibody Clonality

Monoclonal

Storage Note

This purified antibody is stable when stored at 2-8°C. Do not freeze.