CD3, epsilon (Early T Cell Marker) (MaxLight 490)
Catalogue Number: C2253-38A-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Hamster |
| Clone: | 145-2c11 |
| Isotype: | IgG |
| Immunogen: | H-2Kb-specific mouse cytotoxic T lymphocyte. |
| Application: | FC, IF, IP, WB, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. CD3 epsilon, a 20kD transmembrane protein, is a member of the CD3 complex which consists of four subunits, gamma, delta, epsilon and zeta, that are associated to the T cell receptor (TCR). TCR plays a critical role in T cell development and function, and is responsible for ligand recognition. It interacts non-covalently with the CD3 dimers delta/epsilon, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell.
Additional Text
Specificity
Recognizes mouse CD3 epsilon (CD3e) expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation.
Purification
Protein G purified
Antibody Clonality
Monoclonal
C2253-38A-ML490 Datasheet
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PRODUCT
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