CD3, epsilon (Early T Cell Marker)

Catalogue Number: C2253-38A-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Type:Monoclonal Primary Antibody - Unconjugated
Alias:AI504783|CD3|CD3epsilon|T3e|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain
Shipping Condition:Blue Ice
Unit(s): 250 ug, 100 ug
Host name: Hamster
Clone: 145-2c11
Isotype: IgG
Immunogen: H-2Kb-specific mouse cytotoxic T lymphocyte.
Application: FC, IF, IP, WB, IHC

Description

Description: CD3 epsilon, a 20kD transmembrane protein, is a member of the CD3 complex which consists of four subunits, gamma, delta, epsilon and zeta, that are associated to the T cell receptor (TCR). TCR plays a critical role in T cell development and function, and is responsible for ligand recognition. It interacts non-covalently with the CD3 dimers delta/epsilon, gamma/epsilon and zeta/zeta which transduce signals from the TCR into the cell.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

CD3E

Gene ID

12501

Specificity

Recognizes mouse CD3 epsilon (CD3e) expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation.

Purification

Protein G purified

Uniprot ID

P22646

Antibody Clonality

Monoclonal

Price
£760.00


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