CD3, epsilon (Early T Cell Marker) (PE/CY5)
Catalogue Number: C2254-11R-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide and a stabilizing agent. Labeled with PE/CY5. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Rat |
| Clone: | C363.29B (YCD3-1) |
| Isotype: | IgG2c, kappa |
| Immunogen: | IL-4 producing Th2 cell lines including D10 |
| Application: | FC, IP, IHC |
Description
Description: CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chain ranging in size from 16-28kD and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains (1,2). CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. In the presence of Fc receptor-bearing accessory cells, soluble antibody can activate primed and naive T cell in vitro. Immobilized monoclonal antibody can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present (1,3,4). The monoclonal antibody is cytolytic, easily used for cell surface staining and a good immunoprecipitating antibody (1).
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene Name
CD3E
Gene ID
12501
Specificity
Mouse CD3e (Mr 25kD). Recognizes an epitope on the 25kD epsilon chain of the CD3/TCR complex.
Uniprot ID
P22646
Purification
Purified
Antibody Clonality
Monoclonal
C2254-11R Datasheet
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