CD3e (T-cell Surface Glycoprotein CD3 epsilon Chain, T-cell Surface Antigen T3/Leu-4 epsilon Chain, AI504783, CD3epsilon, T3e)

Catalogue Number: C2254-18G-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Type:Monoclonal Primary Antibody - Unconjugated
Alias:AI504783|CD3|CD3epsilon|T3e|T-cell surface antigen T3/Leu-4 epsilon chain|T-cell surface glycoprotein CD3 epsilon chain
Shipping Condition:Blue Ice
Unit(s): 50 ug, 500 ug
Host name: Hamster
Clone: 145-2c11
Isotype: IgG
Immunogen: H-2Kb-specific mouse cytotoxic T lymphocyte
Application: FC, IF, IP, WB, IHC

Description

Description: CD3e is a 20kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3e forms a TCR complex by associating with the CD3d, g and z chains, as well as the TCR a/b or g/d chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

CD3E

Gene ID

12501

Specificity

Recognizes mouse CD3e.

Uniprot ID

P22646

Purification

Affinity Purified

Antibody Clonality

Monoclonal